Disease: Diabetes Mellitus, Non-Insulin-Dependent
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
VPS35 Q96QK1 VPS35 retromer complex component Transporter 0.97 0.656 0.500
USP2 O75604 ubiquitin specific peptidase 2 Enzyme 6.9E-04 0.682 0.462
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TSPO P30536 translocator protein 2.7E-04 0.444 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TFEB P19484 transcription factor EB 0.90 0.527 0.731
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
STXBP3 O00186 syntaxin binding protein 3 Transporter 5.2E-05 0.610 0.769
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SPHKAP Q2M3C7 SPHK1 interactor, AKAP domain containing 0.94 0.695 0.462
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846